Cardinals at Rams – Odds, Lines, and Best Bets

Matthew Stafford: Longest Passing Completion is one of our top picks
Matthew Stafford: Longest Passing Completion is one of our top picks

On Sunday, Oct. 3, the two remaining undefeated teams in the NFC West will do battle at Sofi Stadium as the Arizona Cardinals travel to face the Los Angeles Rams. Both teams sit at 3-0, have youthful head coaches and an exciting playmaking defense as well.

In this article, I will identify the three most profitable bets from the Cardinals-Rams game. Without further ado, let’s dig a little deeper into the matchup:

ARI Cardinals at LA Rams – Odds and Betting Lines


Hopefully, you read my early NFL Week 4 picks against the spread article, where I outlined the Cardinals as a good bet at +6. Well, now we’re all the way down to Cardinals +4.5, and that just further drives the point home that you need to bet some of these games earlier in the week.

There are two very contradictory stats for this matchup, with one favoring each team:

  • Rams have won eight straight meetings against the Cardinals, with seven of them coming by 10+ points. The only misnomer was a seven-point win.
  • Since 2003, when two undefeated divisional opponents meet, the underdog is 24-12-2 ATS (66%).
TeamsSpreadMoney LineTotal
ARI Cardinals+4.5 (-110)+190O55 (-110)
LA Rams-4.5 (-110)-230U55 (-110)

ARI Cardinals at LA Rams – Best Bets


Same Game Parlay: +300

– Cardinals +7.5 (-205)
– Kyler Murray: Over 1.5 Passing TDs (-120)
– Matthew Stafford: Over 298.5 Passing Yards (-115)

We should see plenty of points in this matchup between the two high-flying offenses. If you’d like to add the over into this parlay, go right ahead, but I’ll keep it here for the article’s sake. As mentioned above, I think the Cardinals are a great play at +6 and taking the +7.5 gives us a little leverage on the final score.

As for the quarterbacks, Murray’s passing yardage is always tough to nail down since he is so dynamic with his legs. However, I do believe that he’ll be able to throw the ball into the end zone. Not counting an abbreviated game against the Rams in January last season, Murray has thrown at least two TDs in each of his last two meetings with them. Stafford has thrown for 300+ yards in two of his first three games with LA. This matchup against Arizona works since it runs a Cover-1 defense, meaning a lot the wide receivers can beat the cornerbacks deep.

Robert Woods: Over 59.5 Receiving Yards (-115)

We haven’t seen that breakout game yet from Woods, but I have a feeling it’s coming up this Sunday. As I just mentioned, the Cardinals play a Cover-1 defense, essentially meaning that it’s man-on-man everywhere with one safety up top. This allows Woods to do what he does best, and get across the field in a number of different ways.

Woods has a successful past against Arizona, with four games of at least 80 yards over the last six tries- the last of which was that abbreviated game I talked about with Murray (both teams already had their playoff futures set). Excluding that game, Woods has been targeted at least 11 times in each of the last three games.

Matthew Stafford: Longest Passing Completion – Over 39.5 Passing Yards (-115)

Coming back to the Cardinals’ Cover-1 defense, this will allow the Rams to beat them over the top at least once in this game. LA also had DeSean Jackson in the lineup for the first time last week, giving this team a ridiculous amount of weaponry going forward. With the type of defense the Cardinals play, this will make it tough to match up with all of these talented receivers. I’m willing to bet at least one breaks free for a huge gain.

Al Walsh
Al Walsh Chief Sports Writer